National Institutes of Health SBIR Phase II: NIH SBIR Phase IIB Strategic Breakthrough Award
Amount
$3.0M
Deadline⚠️ Unverified
Apr 6, 2027
Funder
National Institutes of Health
Eligible
for profit
⚠️ Deadline Not Verified — Confirm Before Submitting
This deadline (April 6, 2027) is AI-estimated and has not been confirmed from an official source. It may be inaccurate or outdated. Verify on the funder's official website →
About This Grant
Supports the transition of high-impact technologies toward commercialization.
This is a federal grant announcement. Review these terms and key sections before you start drafting.
A NOFO is the official document a federal agency publishes to announce available grant funding. It is the rulebook for the grant — every requirement, restriction, and evaluation criterion lives in it. Other names for the same thing: FOA, RFA, PA, NOFA, SGA. (RFP usually means a contract, not a grant.)
Eligibility
Who can and cannot apply — confirm your organization type is explicitly listed. Many NOFOs restrict to 501(c)(3)s, specific entity types, or geographic areas.
Deadline
Note the full application deadline AND any required Letter of Intent (LOI) date, which is often 30–60 days earlier.
Funding Amount
Min/max award and total program funding — this sets your budget ceiling. Some NOFOs list an expected number of awards.
Required Attachments
Every form, biosketch, budget narrative, and letter of support — missing even one can trigger automatic rejection. Make a checklist.
Review Criteria
How the application is scored (e.g., 40% significance, 30% approach, 20% investigator, 10% environment). Weight your narrative toward the highest-scoring criteria.
Page Limits
Strict page or character limits per section — exceeding them can disqualify your application. Note the font size, margin, and formatting rules too.
Pro tip: Read the NOFO three times before writing. Most rejected applications fail because the applicant didn't follow the instructions — not because the project was bad.
Full Guided Workflow Available
This grant has a funder website. Start the application to access the step-by-step workflow with Eligibility verification, Quick Start narrative skeleton, PDF upload, AI Writing Coach, and submission tracking.
✅ Test Agent — Import Form + AI Writing Studio
NOFO Writing Guide badge: Click “Open Narrative Step (NOFO Guide)” below — it creates the application and jumps straight to the Narrative step (?step=3) where the expandable NOFO Writing Guide badge appears for federal grants. Expand it to verify.
Option A (recommended): Click the one-click button below — it creates the application, imports sample funder-form questions, generates an LOI, and saves it to the Application record automatically.
Option B (manual): Click "Start Application", then follow the 3-step workflow: (1) Import Funder Form — go to ?step=2, click in-app-form-link, then import-from-funder-website. (2) AI Writing Studio — go to ?step=3, click open-ai-writing-studio, select "Letter of Intent (LOI)", click writing-studio-generate, then save-to-application-btn. (3) Verify the generated LOI text is saved in the Application record.
Start Your Application
Begin your guided application workflow — you can optionally run the AI eligibility check first to see how well you fit.
Generate a section-by-section application guide
Get a lightweight blueprint: section names, suggested lengths, key points to include, strategy tips, and a compliance checklist.
AI will analyze the grant's eligibility criteria, description, and target audience to extract individual requirements.